Tethered FSCV Systems
The TETHERED FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM allows researchers to harness the powerful genetics of the mouse/rat models to address underlying mechanisms of biogenic neurotransmitter release and function. A headmounted FSCV board sends signals through a low-torque commutator to an interface box that streams data to the host PC. The system comes with Pinnacle's FREE FSCV software.
The FSCV interface box provides access to stimulus lines and transmits data to FSCV software.
A low-torque commutator, which is mounted above the cage, allows for unencumbered freedom of movement.
Signals are amplified and filtered at the head of the animal using our headstage, which ensures the delivery of clean, artifact-free data.
Stereotaxically placed guide cannulas allow easy insertion of carbon fiber sensors. Headmounts are affixed to the skull with dental acrylic and act as a connection port for the headstage.
Add Pinnacle's video system to correlate changes in analyte concentration with observable behavior. Different camera options are available.
For new users of our systems, Pinnacle recommends the purchase of an accessory kit. Kits include all necessary one-time-purchases, such as screwdrivers, and enough surgical supplies to complete four surgeries.
|8500-K3: Tethered FSCV Accessory Kit for Mice|
|8500-K7: Tethered FSCV Accessory Kit for Rats|
|Carbon fiber sensors sold separately.|
|#7033: BIO-ONLY HEADMOUNT||#8212:0.12" SCREWS|
|#8254: 23-GAUGE NEEDLE||#9033: BATTERY|
CARBON FIBER SENSORS
Pinnacle's FSCV system uses CARBON FIBER SENSORS (CFSs) to measure the presence of dopamine and other catecholamines in the brains of freely moving animals. All Pinnacle CFSs require an Ag/AgCl reference electrode.
In order to relate the current changes measured by a sensor to actual changes in concentration, it is necessary to calibrate the sensor at the conclusion of an experiment. This process also confirms the integrity and selectivity of the sensor.
|FSCV Calibration Kit||8500-K5|
FSCV SOFTWARE PACKAGE
The FSCV system includes Pinnacle's FREE FSCV software, which supports traditional, short recording paradigms (recordings of two minutes or less) as well as longer-term recordings that use an extended continuous mode. Furthermore, the suite supports integrated, synchronized video recording, which allows monitoring of animal behavior simultaneously with biogenic amine release.
- Features include:
- • Background subtraction
- • 3-D visualization
- • User-selectable filters
- • Heat maps
- • Preprogrammed and custom waveforms
- • Import/export to third-party packages